1.04874

Potassium hydrogen phthalate

for analysis EMSURE^® Reag. Ph Eur

• Synonym(s): Potassium hydrogen phthalate
• Empirical Formula (Hill Notation): C₈H₅KO₄
• CAS Number: 877-24-7
• Molecular Weight: 204.22
• MDL number: MFCD00013070
• UNSPSC Code: 12352106
• EC Index Number: 212-889-4
• NACRES: NA.21

Properties

• Agency: reag. Ph. Eur.
• Quality Level: 300
• product line: EMSURE^®
• Assay: ≥99.5% dry basis (perchloric acid titration)
• form: solid
• potency: >3200 mg/kg LD₅₀, oral (Rat)
• impurities: ≤0.005% In water insoluble matter
• loss: ≤0.2% loss on drying, 105°C
• pH: 4.0 (20 °C, 50 g/L in H₂O)
• mp: 295-300 °C
• density: 1.636 g/cm³
• bulk density: 900 kg/m³
• anion traces: chloride (Cl^-): ≤0.002%; sulfur compounds (as SO₄^2-): ≤0.005%
• cation traces: Cu: ≤0.0002%; Fe: ≤0.0005%; Na: ≤0.01%; Pb: ≤0.0005%; heavy metals (as Pb): ≤0.0005%
• storage temp.: 2-30°C
• InChI: 1S/C8H6O4.K/c9-7(10)5-3-1-2-4-6(5)8(11)12;/h1-4H,(H,9,10)(H,11,12);/q;+1/p-1
• InChI key: IWZKICVEHNUQTL-UHFFFAOYSA-M

Description

Application

• Coulometric method with titratable impurity analysis and mass balance method: This study presents a method to convert acidimetric purity to chemical purity for potassium hydrogen phthalate, which is validated using quantitative nuclear magnetic resonance (qNMR) techniques, enhancing the standards for analytical chemistry (Huang T et al., 2023).


• Triplet states of the nonlinear optical chromophore DCM in single crystals: Investigates the triplet excited states of the nonlinear optical chromophore DCM in potassium hydrogen phthalate single crystals, linking these states to single-molecule dark states, significant for the development of optical materials (Barbon A et al., 2009).

Analysis Note

Assay (Perchloric acid titration from dried substance): ≥ 99.5 %
Identity (IR-spectrum): passes test
In water insoluble matter: ≤ 0.005 %
Chloride (Cl): ≤ 0.002 %
Sulfur compounds (as SO₄): ≤ 0.005 %
Heavy metals (as Pb): ≤ 0.0005 %
Cu (Copper): ≤ 0.0002 %
Fe (Iron): ≤ 0.0005 %
Na (Sodium): ≤ 0.01 %
Pb (Lead): ≤ 0.0005 %
Loss on Drying (105°C): ≤ 0.2 %
Corresponds to Reag. Ph Eur

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): 387.1 °F - Pensky-Martens closed cup
• Flash Point(C): 197.3 °C - Pensky-Martens closed cup