B78203

1-Bromo-1-propene (cis and trans)

98%

• Synonym(s): 1-Propenyl bromide
• Linear Formula: CH₃CH=CHBr
• CAS Number: 590-14-7
• Molecular Weight: 120.98
• Beilstein: 1719096
• EC Number: 209-671-6
• MDL number: MFCD00000186
• UNSPSC Code: 12352100
• PubChem Substance ID: 24892021
• NACRES: NA.22

Properties

• Assay: 98%
• form: liquid
• contains: copper as stabilizer
• refractive index: n20/D 1.4538 (lit.)
• bp: 58-63 °C (lit.)
• mp: −116 °C (lit.)
• density: 1.413 g/mL at 25 °C (lit.)
• SMILES string: C\C=C\Br
• InChI: 1S/C3H5Br/c1-2-3-4/h2-3H,1H3/b3-2+
• InChI key: NNQDMQVWOWCVEM-NSCUHMNNSA-N

Description

Application

1-Bromo-1-propene upon n-BuLi treatment generates the propynyllithium anion, in situ, which later undergoes nucleophilic addition reactions. Some of its other applications are:

• Synthesis of organic reagents such as methyl but-2-ynoate and 1-iodopropyne.
• Preparation o f intermediates in the total synthesis of (+)-aphanamol I and skyllamycins A-C.
• Synthesis of allylated pyrazoles, aryl alkynyl sulfides and allenamides.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H315,H319,H335
• Precautionary Statements: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 39.2 °F - closed cup
• Flash Point(C): 4 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves