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60352

Sigma-Aldrich

Pyrophosphoric acid

≥95% H4P2O7 basis

Synonym(s):

Diphosphoric acid

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About This Item

Linear Formula:
(HO)2P(O)OP(O)(OH)2
CAS Number:
2466-09-3
Molecular Weight:
177.98
EC Number:
219-574-0
MDL number:
MFCD00011343
UNSPSC Code:
12352106
PubChem Substance ID:
24881848
Pricing and availability is not currently available.

Assay

≥95% H4P2O7 basis

impurities

≤0.001% heavy metals (as Pb)

cation traces

Fe: ≤20 mg/kg
Na: ≤20 mg/kg

SMILES string

OP(O)(=O)OP(O)(O)=O

InChI

1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)

InChI key

XPPKVPWEQAFLFU-UHFFFAOYSA-N

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Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H314

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SZBB3330V
SZBB3330

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Bruno Marchand et al.
The Journal of biological chemistry, 282(5), 3337-3346 (2006-12-06)
The pyrophosphate (PPi) analogue phosphonoformic acid (PFA or foscarnet) inhibits the reverse transcriptase (RT) of the human immunodeficiency virus type 1 (HIV-1); however, the mechanisms of drug action and resistance remain elusive. Here we studied the effects of the translocational
Megan H Powdrill et al.
Antimicrobial agents and chemotherapy, 54(3), 977-983 (2009-12-24)
We studied the biochemical mechanisms associated with inhibition and resistance to a 4,5-dihydroxypyrimidine carboxylate that inhibits the hepatitis C virus (HCV) RNA-dependent RNA polymerase NS5B. On the basis of the structure of the pharmacophore, it has been suggested that these
Matthew L Fowler et al.
Eukaryotic cell, 11(10), 1249-1256 (2012-08-21)
Acetate kinase (ACK) catalyzes the reversible synthesis of acetyl phosphate by transfer of the γ-phosphate of ATP to acetate. Here we report the first biochemical and kinetic characterization of a eukaryotic ACK, that from the protist Entamoeba histolytica. Our characterization
James E Dunford et al.
Journal of medicinal chemistry, 51(7), 2187-2195 (2008-03-11)
The nitrogen-containing bisphosphonates (N-BPs) are the main drugs currently used to treat diseases characterized by excessive bone resorption. The major molecular target of N-BPs is farnesylpyrophosphate synthase. N-BPs inhibit the enzyme by a mechanism that involves time dependent isomerization of
Florence Mauger et al.
Human mutation, 34(1), 266-273 (2012-11-08)
Here, we describe a high-throughput, single-tube, allele-specific ribonucleotide analog pyrophosphorolysis-activated polymerization (ribo-PAP) PCR multiplex genotyping and resequencing method. An RNA/DNA chimeric PCR product is generated using genomic DNA as starting template, a panel of allele-selective 5'-tagged primers, a reverse primer
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