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550329

Sigma-Aldrich

6-Bromo-2-methylchromone

97%

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About This Item

Empirical Formula (Hill Notation):
C10H7BrO2
CAS Number:
Molecular Weight:
239.07
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

form

solid

mp

128-132 °C (lit.)

SMILES string

CC1=CC(=O)c2cc(Br)ccc2O1

InChI

1S/C10H7BrO2/c1-6-4-9(12)8-5-7(11)2-3-10(8)13-6/h2-5H,1H3

InChI key

PVHDLBFVSMGZAA-UHFFFAOYSA-N

General description

6-Bromo-2-methylchromone is a 2-methylchromone derivative that can be prepared from ethyl 6-bromo-2-methyl-4-oxo-4H-benzopyran-3-carboxylate via hydrolysis followed by decarboxylation.

Application

6-Bromo-2-methylchromone may be used in the preparation of 6-bromochromone-2-carboxaldehyde via oxidation using selenium dioxide.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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A highly practical route to 2-methylchromones from 2-acetoxybenzoic acids.
Jung JC, et al.
Synthetic Communications, 31(12), 1837-1845 (2001)
Selective C-3 monochlorination of 2-methylchromones and chromone-2-carboxaldehydes.
Jagadeesh SG, et al.
Synthetic Communications, 28(20), 3827-3833 (1998)

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