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Sigma-Aldrich

Poly(methyl vinyl ether-alt-maleic anhydride)

average Mw ~1,080,000, average Mn ~311,000

Synonym(s):

maleated copolymer, maleated polymer, maleic copolymer

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About This Item

Linear Formula:
(C4H2O3 · C3H6O)n
CAS Number:
9011-16-9
MDL number:
MFCD00134013
UNSPSC Code:
12162002
PubChem Substance ID:
329756128
NACRES:
NA.23

form

powder

mol wt

average Mn ~311,000
average Mw ~1,080,000

impurities

<2% benzene

solubility

H2O: soluble (upon hydrolysis)
organic solvents: soluble

InChI

1S/C4H2O3.C3H6O/c5-3-1-2-4(6)7-3;1-3-4-2/h1-2H;3H,1H2,2H3

InChI key

UPBDXRPQPOWRKR-UHFFFAOYSA-N

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Application

Poly(methyl vinyl ether-alt-maleic anhydride) P(MVE-MA) can be used:
  • To prepare antimicrobial hydrogels with good mechanical strength, adhesiveness to the skin, and excellent swelling ability. For example, autoclaved mixtures of P(MVE-MA) and PVA (polyvinyl alcohol) can inhibit bacteria growth against Staphylococcus aureus.
  • As an electrolyte additive for stabilizing the interface of high-voltage layered Li-rich oxides (LLROs). P(MVE-MA) can absorb more H2O from the electrolyte and suppress the oxidative decomposition of the electrolyte.
  • To functionalize electrospun PVA nanofibers for protein adsorption. These modified nanofibrous membranes can be used for protein purification.
  • To synthesize separator membranes with good ionic conductivity. These membranes keep the positive and negative electrodes apart and prevent electrical short circuits.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H319,H340,H350,H373

Hazard Classifications

Carc. 1A - Eye Irrit. 2 - Muta. 1B - Skin Irrit. 2 - STOT RE 2

Target Organs

Blood

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sigma-Aldrich

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Sebastian G Ciancio
Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 32(1), 70-76 (2011-04-06)
This review summarizes research that has assessed the effectiveness of various antimicrobial-containing dentifrices in preventing and/or reducing a number of oral health problems facing our patients today. The results of these studies indicate that, when compared with a conventional fluoride
Superior management of plaque and gingivitis through the use of a triclosan/copolymer dentifrice.
Sebastian Ciancio et al.
The Journal of clinical dentistry, 21(4), 93-95 (2011-01-29)
Suru Mankodi et al.
American journal of dentistry, 24 Spec No A, 21A-27A (2012-01-06)
To investigate the efficacy of a dentifrice containing 0.3% triclosan, 2.0% PVM/MA copolymer, 0.243% sodium fluoride, and specially-designed silica in controlling established dental plaque and gingivitis. Qualifying adult male and female subjects from the West Palm Beach, Florida area were
Xuejun Liu et al.
Journal of dentistry, 39(4), 293-301 (2010-11-09)
To study the effectiveness of a dentifrice containing polymethyl vinyl ether-maleic acid (PVM/MA) copolymer in a silica base in occluding dentin tubules for treatment of dentin sensitivity. Thirty-two human dentin discs were divided into two groups and brushed in the
A I Camacho et al.
Vaccine, 29(41), 7130-7135 (2011-06-10)
Adjuvant research is being oriented to TLR-agonists, but complement activation has been relatively unexplored. In previous studies it was demonstrated that poly(methyl vinyl ether-co-maleic anhydride) nanoparticles (PVMA NPs) used as adjuvant differentially activate dendritic cells through toll like receptors (TLR)
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