31546

N,N-Diacetyl-O-methylhydroxylamine

≥95.0%

• Synonym(s): N-Acetyl-N-methoxyacetamide, N-Methoxydiacetamide
• Empirical Formula (Hill Notation): C₅H₉NO₃
• CAS Number: 128459-09-6
• Molecular Weight: 131.13
• Beilstein: 3537117
• MDL number: MFCD00191669
• UNSPSC Code: 12352111
• PubChem Substance ID: 57648583

Properties

• Assay: ≥95.0%
• reaction suitability: reaction type: C-C Bond Formation
• refractive index: n20/D 1.447
• density: 1.12 g/mL at 20 °C (lit.)
• SMILES string: CON(C(C)=O)C(C)=O
• InChI: 1S/C5H9NO3/c1-4(7)6(9-3)5(2)8/h1-3H3
• InChI key: HWZKQIRJZPOEQF-UHFFFAOYSA-N

Description

Application

Reactant for:

• Preparation of benzamide derivatives as rally available antitumor agents
• Synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors
• Acetylation of amines (acetylating agent)

Other Notes

Chemoselective acetylating agent for prim. amines in the presence of sec. amines and alcohols

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 186.8 °F - closed cup
• Flash Point(C): 86 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves