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About This Item
Empirical Formula (Hill Notation):
C9H10BrNO2
CAS Number:
Molecular Weight:
244.09
Beilstein:
2212159
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
≥98.0% (NT)
form
solid
optical activity
[α]20/D −22.0±2°, c = 0.5% in H2O
reaction suitability
reaction type: solution phase peptide synthesis
mp
~265 °C (dec.)
application(s)
peptide synthesis
SMILES string
N[C@@H](Cc1ccc(Br)cc1)C(O)=O
InChI
1S/C9H10BrNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m0/s1
InChI key
PEMUHKUIQHFMTH-QMMMGPOBSA-N
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Thermal neutron capture therapy: the Japanese-Australian clinical trial for malignant melanoma.
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Introduction of a yeast suppressor tRNA (ytRNA(Phe)(CUA)) and a mutant yeast phenylalanyl-tRNA synthetase (yPheRS (T415G)) into an Escherichia coli expression host allows in vivo incorporation of phenylalanine analogues into recombinant proteins in response to amber stop codons. However, high-fidelity incorporation
Dose fractionation in neutron capture therapy for malignant melanoma.
B J Allen et al.
Basic life sciences, 50, 63-67 (1989-01-01)
M Ibba et al.
FEBS letters, 364(3), 272-275 (1995-05-15)
It has previously been demonstrated that the unnatural amino acid p-Cl-phenylalanine can be attached to tRNA(Phe) by a modified phenylalanyl-tRNA synthetase with relaxed amino acid substrate specificity. We show that this modification to the translational machinery of Escherichia coli is
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