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Merck

CACNB2

calcium channel, voltage-dependent, beta 2 subunit

Synonyms:
CACNLB2, CAVB2, MYSB
Species:
UniProtKB ID:
Gene ID:
  • Human(783) Summary: This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Feb 2013]
  • Mouse(12296) calcium channel, voltage-dependent, beta 2 subunit
  • Rat(116600) calcium channel, voltage-dependent, beta 2 subunit
  • domestic guinea pig(100192393) calcium channel, voltage-dependent, beta 2 subunit
  • naked mole-rat(101713647) calcium channel, voltage-dependent, beta 2 subunit
  • Domestic Rabbit(100009277) calcium channel, voltage-dependent, beta 2 subunit
  • cow(327667) calcium channel, voltage-dependent, beta 2 subunit
  • sheep(101112498) calcium channel, voltage-dependent, beta 2 subunit
  • dog(487113) calcium channel, voltage-dependent, beta 2 subunit
  • domestic cat(101093028) calcium channel, voltage-dependent, beta 2 subunit
  • Horse(100055971) calcium channel, voltage-dependent, beta 2 subunit
  • chicken(428420) calcium channel, voltage-dependent, beta 2 subunit

Custom & Knockdown Gene Products

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Species
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Gabapentin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Gabapentin, solid,
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CACNB2 antibody produced in mouse, clone S8B-1, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-CACNB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-CACNB2 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, rat
Application
ELISA
western blot
Anti-Calcium Channel (β2 subunit) (Voltage Gated Ca2+ Channel) antibody produced in rabbit, ~1 mg/mL, fractionated antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
western blot

Small Molecule - Blocker

Product Number
Description
Species
Bepridil hydrochloride, powder,
Species
human
Terodiline hydrochloride, ≥98% (HPLC), solid,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CACNB2,
Species
human
MISSION® esiRNA, targeting mouse Cacnb2,
Species
mouse