An unexpected silver triflate catalyzed reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate.

An unexpected silver triflate catalyzed reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate.

Organic letters (2012-05-24)

Danqing Zheng, Shaoyu Li, Jie Wu

RESUMEN

An unexpected silver triflate catalyzed reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate provides an efficient route for the generation of isoquinolines. The reaction proceeds smoothly in air under mild conditions with high efficiency.

MATERIALES

Referencia del producto

Marca

Descripción del producto

290068

Sigma-Aldrich

Zinc trifluoromethanesulfonate, 98%

347817

Sigma-Aldrich

Trifluoromethanesulfonic acid, ReagentPlus^®, ≥99%

176435

Sigma-Aldrich

Silver trifluoromethanesulfonate, ≥99%

515884

Sigma-Aldrich

Aluminum trifluoromethanesulfonate, 99.9% trace metals basis

481548

Sigma-Aldrich

Lithium trifluoromethanesulfonate, 99.995% trace metals basis

483346

Sigma-Aldrich

Silver trifluoromethanesulfonate, ≥99.95% trace metals basis

430609

Sigma-Aldrich

Lanthanum(III) trifluoromethanesulfonate, 99.999% trace metals basis

282669

Sigma-Aldrich

Lithium trifluoromethanesulfonate, 96%

158534

Sigma-Aldrich

Trifluoromethanesulfonic acid, reagent grade, 98%

85325

Sigma-Aldrich

Silver trifluoromethanesulfonate, purum, ≥98.0% (Ag)