1612903

Sitagliptin phosphate

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: Sitagliptin phosphate monohydrate, 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate, MK-0431
• Fórmula empírica (notación de Hill): C₁₆H₁₅F₆N₅O · H₃PO₄ · H₂O
• Número CAS: 654671-77-9
• Peso molecular: 523.32
• MDL number: MFCD10001393
• UNSPSC Code: 41116107
• NACRES: NA.24
• eCl@ss: 25140904

Propiedades

• grade: pharmaceutical primary standard
• agency: USP
• API family: sitagliptin
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule); pharmaceutical; pharmaceutical
• format: neat
• storage temp.: 2-8°C
• SMILES string: FC(F)(F)c1[n]2c(nn1)CN(CC2)C(=O)C[C@H](N)Cc3c(cc(c(c3)F)F)F.[P](=O)(O)(O)O.O
• InChI: 1S/C16H15F6N5O.H3O4P.H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22;1-5(2,3)4;/h4,6,9H,1-3,5,7,23H2;(H3,1,2,3,4);1H2/t9-;;/m1../s1
• InChI key: GQPYTJVDPQTBQC-KLQYNRQASA-N

Descripción

General description

Find answers to frequently asked questions on USP products in USP FAQs.

An anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release, stimulates insulin release and lowers blood glucose.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sitagliptin phosphate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Sitagliptin Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08,GHS07
• Palabra de advertencia: Warning
• Códigos de peligro: H319,H373
• Indicaciones de precaución: P260 - P264 - P280 - P305 + P351 + P338 - P314 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - STOT RE 2
• Órganos diana: Liver
• Clase de almacenamiento: 11 - Combustible Solids
• WGK: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable