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Merck

18127

Supelco

1,1,1,3,3,3-Hexafluoro-2-propanol

1,1,1,3,3,3-Hexafluoro-2-propanol
1 of 1 reviewers received a sample product or took part in a promotion

for LC-MS LiChropur

Sinónimos:

HFP, Hexafluoroisopropanol

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About This Item

Fórmula lineal:
(CF3)2CHOH
Número de CAS:
Peso molecular:
168.04
Beilstein:
1841007
Número MDL:
Código UNSPSC:
12352104
NACRES:
NA.21
En este momento no podemos mostrarle ni los precios ni la disponibilidad

Ensayo

≥99.8% (GC)

Formulario

liquid

calidad

for LC-MS LiChropur

impurezas

≤0.02% water

índice de refracción

n20/D 1.275 (lit.)

bp

59 °C (lit.)

mp

−4 °C (lit.)

densidad

1.596 g/mL at 25 °C (lit.)

trazas de catión

Al: ≤0.5 ppm
Ca: ≤0.5 ppm
Cu: ≤0.02 ppm
Fe: ≤0.1 ppm
K: ≤2 ppm
Mg: ≤0.1 ppm
Na: ≤10 ppm

idoneidad

passes test for LC-MS (ESI/APCI pos. < 10 ppb)

cadena SMILES

OC(C(F)(F)F)C(F)(F)F

InChI

1S/C3H2F6O/c4-2(5,6)1(10)3(7,8)9/h1,10H

Clave InChI

BYEAHWXPCBROCE-UHFFFAOYSA-N

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Descripción general

1,1,1,3,3,3-Hexafluoro-2-propanol(HFIP) is a thermally stable, highly polar, UV-transparent solvent that is misciblewith water and many polar organic solvents. It is used as a mobile phaseadditive in liquid chromatography-mass spectrometry (LC-MS) method to improveseparation and detection.[1][2]

Aplicación

1,1,1,3,3,3-Hexafluoro-2-propanol can be used as a:
  • Buffer additive for LC-ESI-MS to separate acidic and basic compounds.[3]
  • Eluent additive in the UHPLC-MS/MS method to improve the chromatographic separation of basic and zwitterionic compounds.

Información legal

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Producto relacionado

Referencia del producto
Descripción
Precios

Pictogramas

Health hazardCorrosion

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Eye Dam. 1 - Repr. 2 - Skin Corr. 1A - STOT RE 2 Oral

Órganos de actuación

Central nervous system

Código de clase de almacenamiento

8A - Combustible corrosive hazardous materials

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

No data available

Punto de inflamabilidad (°C)

No data available


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Certificados de análisis (COA)

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Visite la Librería de documentos

1, 1, 1, 3, 3, 3-Hexafluoro-2-propanol
Phillips AJ and Roach JJ
e-EROS Encyclopedia of Reagents for Organic Synthesis, 1-9 (2001)
Fluoroalcohols as novel buffer components for basic buffer solutions for liquid chromatography electrospray ionization mass spectrometry: retention mechanisms
Kipper K, et al.
Journal of Chromatography A, 1218(45), 8175-8180 (2011)
Retention mechanisms of acidic and basic analytes on the Pentafluorophenyl stationary phase using fluorinated eluent additives
Lossmann K, et al.
Journal of Chromatography A, 1666, 462850-462850 (2022)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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Reviews

1 of 1 reviewers received a sample product or took part in a promotion

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