V3265

VU0029767

≥98% (HPLC)

• Sinónimos: (E)-2-(4-Ethoxyphenylamino)-N′-((2-hydroxynaphthalen-1-yl)methylene)acetohydrazide
• Fórmula empírica (notación de Hill): C₂₁H₂₁N₃O₃
• Número de CAS: 326001-01-8
• Peso molecular: 363.41
• MDL number: MFCD01206089
• UNSPSC Code: 12352200
• PubChem Substance ID: 329829043

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• color: gray-brown
• solubility: DMSO: >10 mg/mL
• storage temp.: room temp
• SMILES string: CCOc1ccc(NCC(=O)N\N=C\c2c(O)ccc3ccccc23)cc1
• InChI: 1S/C21H21N3O3/c1-2-27-17-10-8-16(9-11-17)22-14-21(26)24-23-13-19-18-6-4-3-5-15(18)7-12-20(19)25/h3-13,22,25H,2,14H2,1H3,(H,24,26)/b23-13+
• InChI key: JWRJGCUSLSJMMD-YDZHTSKRSA-N

Descripción

Biochem/physiol Actions

VU0029767 is a selective, positive allosteric modulator at the muscarinic M1 acetylcholine receptor. It shifts concentration-dependent response to acetylcholine at least five-fold, but does not compete at the ACh binding site. VU0029767 also potentiates the effects of allosteric agonist TBPB.

Información de seguridad

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H302,H315,H319,H335,H410
• pcodes: P261 - P264 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable