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T3080

Sigma-Aldrich

Beta-Thromboglobulin from human platelets

≥95% (SDS-PAGE)

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About This Item

MDL number:
UNSPSC Code:
12352202
NACRES:
NA.25

biological source

human platelets

Quality Level

assay

≥95% (SDS-PAGE)

form

solution

mol wt

tetramer 35,800 Da

technique(s)

cell culture | mammalian: suitable

shipped in

dry ice

storage temp.

−70°C

Application

Plasma levels of β-thromboglobulin directly correlate to the level of platelet activity and can be measured to determine platelet activity.

Biochem/physiol Actions

β-thromboglobulin was shown to inhibit megakaryocyte colony formation C.
Heparin binding protein that is used as a platelet activation marker.

Physical form

Supplied as a solution in 25 mM Hepes and 150 mM NaCl, pH 7.4

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

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C W Pumphrey et al.
The American journal of cardiology, 50(6), 1258-1261 (1982-12-01)
The plasma concentration of beta-thromboglobulin (BTG), a platelet-specific protein released during platelet aggregation, is considered a sensitive marker of in vivo platelet activity. The mean plasma level in 133 asymptomatic individuals was 32.3 +/- 1.1 ng/ml, and there was no
J F Abgrall et al.
Experimental hematology, 19(3), 202-205 (1991-03-01)
The effect of highly purified human beta-thromboglobulin (beta TG), a glycoprotein present in platelet alpha granules, was tested on human bone marrow in vitro megakaryocyte (MK) colony formation. A concentration of 5 micrograms/ml of beta TG induced a 50% reduction

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