Saltar al contenido
Merck
Todas las fotos(1)

Documentos

T2903

Sigma-Aldrich

Trp-His-Trp-Leu-Gln-Leu

≥97% (HPLC)

Sinónimos:

α1-Mating factor fragment 1-6

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C45H59N11O8
Número de CAS:
65418-88-4
Peso molecular:
882.02
MDL number:
MFCD00133882
UNSPSC Code:
51111800
PubChem Substance ID:
24900091
NACRES:
NA.32

biological source

synthetic (organic)

Quality Level

200

assay

≥97% (HPLC)

form

powder

storage temp.

−20°C

SMILES string

CC(C)CC(NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc3cnc[nH]3)NC(=O)C(N)Cc4c[nH]c5ccccc45)C(O)=O

InChI

1S/C45H59N11O8/c1-24(2)15-35(42(60)52-34(13-14-39(47)57)41(59)56-38(45(63)64)16-25(3)4)54-43(61)36(18-27-21-50-33-12-8-6-10-30(27)33)55-44(62)37(19-28-22-48-23-51-28)53-40(58)31(46)17-26-20-49-32-11-7-5-9-29(26)32/h5-12,20-25,31,34-38,49-50H,13-19,46H2,1-4H3,(H2,47,57)(H,48,51)(H,52,60)(H,53,58)(H,54,61)(H,55,62)(H,56,59)(H,63,64)

InChI key

PBLMMVDDGREFKH-UHFFFAOYSA-N

Amino Acid Sequence

Trp-His-Trp-Leu-Gln-Leu

Application

Trp-His-Trp-Leu-Gln-Leu (WHWLQL) was used as an internal standard in multiplex serum protein assay for evaluating the individual′s probability of having colorectal cancer (CRC).

Biochem/physiol Actions

Trp-His-Trp-Leu-Gln-Leu (WHWLQL) is the peptide fragment of alpha1-mating factor secreted by yeast that facilitates in the regulation of mating. Alpha1-mating factor can arrest many yeast strains in the G1-phase of the cell cycle.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

C B Xue et al.
International journal of peptide and protein research, 47(3), 131-141 (1996-03-01)
Analogs of the Saccharomyces cerevisiae alpha-mating factor, Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr, where Lys7 and Gln10 were replaced with Cys, Cys(CH3), or Ser, were synthesized using solid-phase procedures on a phenylacetamidomethyl resin. Cyclo7,10[Cys7,X9,Cys10,Nle12]alpha-factor , where X=D-Val, D-Ala, L-Ala and Gly, were prepared by on-resin
Randall Brock et al.
American journal of cancer research, 2(5), 598-605 (2012-09-08)
Our purpose is to develop a serum assay to determine an individual's probability of having colorectal cancer (CRC). We have discovered a protein panel yielding encouraging, clinically significant results. We evaluated 431 serum samples from donors screened for CRC by
W Siede et al.
Mutation research, 245(4), 287-292 (1990-12-01)
Synchronously dividing haploid yeast cells were UV-irradiated in various stages of the cell cycle after release from alpha-factor arrest. In confirmation of earlier results (Chanet et al., 1973), in wild-type strains G1/S phase cells were found to be the most

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico