This product is sourced from rice as stated on the product detail page.
T0452
D-α-Tocotrienol
from rice, ≥75% (GC)
Sinónimos:
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol
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About This Item
Fórmula empírica (notación de Hill):
C29H44O2
Número de CAS:
Peso molecular:
424.66
Código UNSPSC:
12352205
NACRES:
NA.79
En este momento no podemos mostrarle ni los precios ni la disponibilidad
Productos recomendados
origen biológico
rice
Nivel de calidad
Ensayo
≥75% (GC)
Formulario
liquid
color
colorless to brown
mp
30-31 °C
temp. de almacenamiento
−20°C
cadena SMILES
O1[C@@](CCc2c1c(c(c(c2C)O)C)C)(CC\C=C(\CC\C=C(\CCC=C(C)C)/C)/C)C
InChI
1S/C29H44O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h12,14,16,30H,9-11,13,15,17-19H2,1-8H3/b21-14+,22-16+/t29-/m1/s1
Clave InChI
RZFHLOLGZPDCHJ-XZXLULOTSA-N
Categorías relacionadas
Descripción general
Acciones bioquímicas o fisiológicas
α-Tocotrienol is an effective free radical scavengerand elicits protective functionality during oxidative stress in microsomes.[1] It is a strong antioxidant,[2] which reduces inflammation[4] and is used in cancer treatment.[3] α-tocotrienol supplementation may reduce cholesterol levels in hypercholesterolemia.[3] α-tocotrienol is neuroprotective as it blocks glutamate-induced cell death in neuronal cells.[5]
α-Tocotrienol may be used along with other isoforms to differentiate tocotrienol activities.
Tocotrienols are widely utilized for their strong antioxidant properties. The various isoforms of tocotrienols differ in their methyl substitution in the chromanol head. α-tocotrienol demonstrates neuroprotective properties by blocking glutamate-induced cell death in neuronal cells.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Molecular aspects of alpha-tocotrienol antioxidant action and cell signalling
Packer L, et al.
The Journal of Nutrition, 131(2), 369S-373S (2001)
Vladimir Gogvadze et al.
International journal of cancer, 127(8), 1823-1832 (2010-01-28)
Release of mitochondrial proteins such as cytochrome c, AIF, Smac/Diablo etc., plays a crucial role in apoptosis induction. A redox-silent analog of vitamin E, alpha-tocopheryl succinate (alpha-TOS), was shown to stimulate cytochrome c release via production of reactive oxygen species
Tocotrienols inhibit lipopolysaccharide-induced pro-inflammatory cytokines in macrophages of female mice
Qureshi AA, et al.
Lipids in Health and Disease, 9(1), 143-143 (2010)
Tocotrienol is a cardioprotective agent against ageing-associated cardiovascular disease and its associated morbidities
Ramanathan N, et al.
Nutrition & Metabolism, 15(1), 6-6 (2018)
Han-A Park et al.
Stroke, 42(8), 2308-2314 (2011-07-02)
α-Tocotrienol (TCT) represents the most potent neuroprotective form of natural vitamin E that is Generally Recognized As Safe certified by the U.S. Food and Drug Administration. This work addresses a novel molecular mechanism by which α-TCT may be protective against
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what is the source of Tocotrienol rice or rice bran oil
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