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SRP6560

Sigma-Aldrich

Wnt-2 human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Sinónimos:

INT1L1, IRP, Int-1-like protein 1, Int-1-related protein

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

assay

≥90% (SDS-PAGE)

form

lyophilized

mol wt

39.9 kDa

packaging

pkg of 1 mg
pkg of 10 μg
pkg of 50 μg

UniProt accession no.

P09544

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... WNT2(7472)

Biochem/physiol Actions

Wnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis.[1] Wnt family member-2 (Wnt-2) has a role in activating β-catenin.[2] It has been shown to have a role in cardiogenesis.[3] The protein is overexpressed in tumors and cancers.[4][1]

Physical form

Lyophilized without additives.

Reconstitution

Reconstitute in sterile ddH2O to a concentration ≥ 100 μg/mL.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Steven Hyman
Autism: The Science of Mental Health (2013)
Wnt2 as a new therapeutic target in malignant pleural mesothelioma
Julien Mazieres
International Journal of Cancer. Journal International Du Cancer (2005)
Wnt2 complements Wnt/?-catenin signaling in colorectal cancer
Youn-Sang Jung
Oncotarget, 6(35), 37257-37268 (2015)
Overexpression of Wnt-2 in colorectal cancers.
Park JK
Neoplasma, 56(2), 119-123 (2009)
Wnt signal transduction pathways
Yuko Komiya
Organogenesis, 4(2), 68-75 (2008)
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