SRP6206

sCD22 human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• Sinónimos: B Lymphocyte cell adhesion molecule, BL-CAM, Leu-14, Siglec-2
• Código UNSPSC: 12352200
• NACRES: NA.32

Propiedades

• origen biológico: human
• recombinante: expressed in E. coli
• Ensayo: ≥98% (SDS-PAGE)
• Formulario: lyophilized powder
• mol peso: ~75 kDa
• envase: pkg of 10 μg; pkg of 50 μg
• impurezas: <1 EU/μg endotoxin (LAL test)
• Nº de acceso UniProt: P20273
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... CD22(933)

Descripción

Descripción general

CD22 is a B-lineage restricted 135 kDa glycoprotein whose cell surface expression is limited to resting and activated B lymphocytes. The physiological role of CD22 is still unknown. Targeted disruption of CD22 in mice results in a reduced level of surface IgM on peripheral B cells suggesting a role for CD22 in limiting antigen receptor signaling. CD22 is a member of the Ig gene superfamily that uniquely binds a sialic acid-dependent ligand. Recombinant human CD22 is a soluble 75.0 kDa protein which corresponds to the extracellular domain of CD22.

Forma física

Sterile filtered through a 0.2 micron filter. Lyophilized from 1X PBS, pH 7.2.

Reconstitución

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Información de seguridad

• Código de clase de almacenamiento: 13 - Non Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable