SRP0697

TAU-316 Protein

recombinant

• Código UNSPSC: 12352202
• NACRES: NA.77

Propiedades

• recombinante: expressed in E. coli
• Ensayo: 70-95% (SDS-PAGE)
• Formulario: frozen liquid
• mol peso: ~39 kDa
• concentración: 0.2 μg/μL
• nº de acceso: P10636-3
• Condiciones de envío: dry ice
• temp. de almacenamiento: −70°C
• Información sobre el gen: human ... MAPT(4137)

Descripción

Aplicación

Useful for kinase assay and Western blot.

Acciones bioquímicas o fisiológicas

Recombinant full-length human tag-free Tau-316 was expressed in E. coli cells. Tau-316 encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. Tau-316 transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type ⁽¹⁾. Tau-316 gene mutations have been associated with several neurodegenerative disorders such as Alzheimer′s disease, Pick′s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy ⁽²⁾.

Secuencia

Full Length

Reconstitución

Formulated in 50mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

Almacenamiento y estabilidad

Store in aliquots at -70°C. Avoid freeze/thaw cycles.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable