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SML3198

Ac2-26 trifluoroacetate

≥98% (HPLC)

Sinónimos:

Ac2-26 TFA, LC1 trifluoroacetate, Lipocortin 1- trifluoroacetate, Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH trifluoroacetate, Annexin A1 trifluoroacetate, AnxA1 trifluoroacetate

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Talla/SKUDisponibilidadPrecio
1 mg
Comprobar disponibilidad del carrito
MXP 2,549.00

Acerca de este artículo

Fórmula empírica (notación de Hill):
C141H210N32O44S
Peso molecular:
3089.43
NACRES:
NA.77
UNSPSC Code:
12352107
Assay:
≥98% (HPLC)
Form:
powder

MXP 2,549.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to off-white

storage temp.

−20°C

General description

Ac2-26 is a Lipocortin 1/Annexin 1 Peptide Mimetic, derived from the N-terminal region of annexin A1 (AnxA1). It contains residues 2–26 of AnxA1. Ac2-26 activates formyl peptide receptor family members formyl peptide receptor (FPR), FPR-like (FPRL) 1 and FPRL2. It exhibits an anti-inflammatory effect by inhibiting the adhesion and transmigration of leukocytes (leukocyte extravasation). This facilitates the growth and migration of epithelial cells, aiding in tissue repair. Ac2-26 also serves as a cardioprotective peptide. It is observed that Ac2-26 reduces acute lung injury caused by ischemia and reperfusion.

Biochem/physiol Actions

Lipocortin 1/Annexin 1 Peptide Mimetic; activates formyl peptide receptor family

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Este artículo
B4272SML2836T0675
description

≥98% (HPLC)

description

≥97% (HPLC)

description

≥95% (HPLC)

description

≥97% (HPLC)

form

powder

form

powder

form

lyophilized powder

form

powder

assay

≥98% (HPLC)

assay

≥97% (HPLC)

assay

≥95% (HPLC)

assay

≥97% (HPLC)

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

color

white to off-white

color

-

color

white to beige

color

-


Clase de almacenamiento

11 - Combustible Solids

¿Qué está pasando?

WGK 3

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)

Not applicable



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Questions

1–2 of 2 Questions  
  1. What is the solubility of the product SML3198, Ac2-26 trifluoroacetate?

    1 answer
    1. The solubility of this product has not been tested by QC, and there is no solubility information available in our database or COA. However, according to a Google search, the solubility of Ac2-26 trifluoroacetate is as follows:
      In Vitro:
      - H2O: 0.11 mg/mL (0.03 mM; ultrasonic and adjust pH to 13 with NaOH)
      - DMSO: < 1 mg/mL (ultrasonic) (insoluble or slightly soluble)
      In Vivo:
      - Solvent 1: PBS
      - Solubility: 1 mg/mL (0.31 mM)
      - Clarity: Clear solution
      - Requirements: Ultrasonic and adjust pH to 9 with NaOH

      Helpful?

  2. Ac2-26 trifluoroacetate ≥98% (HPLC) (sigmaaldrich.com) 上記を購入したのですが、溶かす溶媒は蒸留水で良いのでしょうか?またストックする濃度についても教えてください。

    1 answer
    1. The solubility of this product is not determined. However, other sources suggest that this compound is soluble in Phosphate Buffered Saline at 1 mg/mL. Sonication or increasing the pH to 9 by adding NaOH drop-wise may be required.

      Helpful?

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