SML2558

N-arachidonoylglycine

≥98% (HPLC)

• Sinónimos: N-[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]-glycine
• Fórmula empírica (notación de Hill): C₂₂H₃₅NO₃
• Número de CAS: 179113-91-8
• Peso molecular: 361.52
• UNSPSC Code: 12352211
• NACRES: NA.77

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated; protect from light
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)NCC(O)=O
• InChI: 1S/C22H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21(24)23-20-22(25)26/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-20H2,1H3,(H,23,24)(H,25,26)/b7-6-,10-9-,13-12-,16-15-
• InChI key: YLEARPUNMCCKMP-DOFZRALJSA-N

Descripción

Biochem/physiol Actions

Arachidonylglycine (NAGly) is a metabolite of the endocannabinoid anandamide (AEA) that binds to G-protein coupled receptor 18 (GPR18). It is an endogenous inhibitor of fatty acid amide hydrolase (FAAH), and also shown to be an inhibitor of the glycine transporter GlyT2. NAGly is involved in a number of pathways associated with analgesic activity and has exhibited analgesic properties in a rat model of inflammatory pain

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: No data available
• flash_point_c: No data available