The stability of this material in solution has not been evaluated. For optimum results, stock solutions should be prepared fresh. However, external sources indicate that stock solutions prepared in DMSO, and purged with inert gas, may be stored for up to 1 year at -20°C and up to 2 years at -80°C, in working aliquots. Avoid repeated freeze/thaw cycles. This information has not been validated.
SML1682
CDN1163
≥98% (HPLC), SERCA activator, powder
Sinónimos:
4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)-benzamide
Iniciar sesión para ver los precios por organización y contrato.
Seleccione un Tamaño
Cambiar Vistas
| Talla/SKU | Disponibilidad | Precio |
|---|---|---|
5 mg | Comprobar disponibilidad del carrito | MXP 2,614.00 |
25 mg | Comprobar disponibilidad del carrito | MXP 10,531.00 |
Acerca de este artículo
Fórmula empírica (notación de Hill):
C20H20N2O2
Número CAS:
Peso molecular:
320.39
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarleNombre del producto
CDN1163, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
CC1=NC2=C(NC(C3=CC=C(OC(C)C)C=C3)=O)C=CC=C2C=C1
InChI
1S/C20H20N2O2/c1-13(2)24-17-11-9-16(10-12-17)20(23)22-18-6-4-5-15-8-7-14(3)21-19(15)18/h4-13H,1-3H3,(H,22,23)
InChI key
GVGVYDCVFBGALZ-UHFFFAOYSA-N
Biochem/physiol Actions
CDN1163 is an allosteric activator of sarco/ endoplasmic reticulum Ca2+-ATPase (SERCA) that potently lowered fasting blood glucose, improved glucose tolerance and ameliorated hepatosteatosis in ob/ob mice. Additionally CDN1163 induces significant reduction in adipose tissue weight with no change in lean mass in ob/ob mice. CDN1163 has no effect on glucose levels or body weight in lean control mice.
CDN1163 is an allosteric activator of sarco/ endoplasmic reticulum Ca2+-ATPase (SERCA).
CDN1163 treatment declined the hepatic expression of genes implicated in gluconeogenesis and lipogenesis as well as attenuated endoplasmic reticulum (ER) stress response and ER stress-induced apoptosis. CDN1163 interacts with sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) and enhances ER Ca2+ content.
Clase de almacenamiento
11 - Combustible Solids
¿Qué está pasando?
WGK 3
Punto de inflamación (°F)
Not applicable
Punto de inflamación (°C)
Not applicable
Elija entre una de las versiones más recientes:
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
-
After reconstitution in DMSO, what are the recommended storage conditions and expected stability?
1 answer-
Helpful?
-