SML1616

ICA-069673

≥98% (HPLC)

• Sinónimos: ICA 069673, N-(2-Chloro-5-pyrimidinyl)-3,4-difluoro-benzamide
• Fórmula empírica (notación de Hill): C₁₁H₆ClF₂N₃O
• Número de CAS: 582323-16-8
• Peso molecular: 269.63
• MDL number: MFCD20926351
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825502
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: room temp
• SMILES string: O=C(C1=CC=C(F)C(F)=C1)NC2=CN=C(Cl)N=C2
• InChI: 1S/C11H6ClF2N3O/c12-11-15-4-7(5-16-11)17-10(18)6-1-2-8(13)9(14)3-6/h1-5H,(H,17,18)
• InChI key: IIBSHMFXVWTQSJ-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

ICA-069673 has higher selectivity towards KV7.2/KV7.3 heterodimeric channels than KV7.3/KV7.5 channels. ICA-069673 is considered as a part of gating modifiers.[1]

ICA-069673 is an orally active, potent and selective KV7.2/KV7.3 (KCNQ2/Q3) channel opener that is active in rodent epilepsy models.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3