SML1487

ABT-089 dihydrochloride

≥98% (HPLC)

• Sinónimos: 2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride, Pozanicline dihydrochloride
• Fórmula empírica (notación de Hill): C₁₁H₁₆N₂O · 2HCl
• Número de CAS: 161416-61-1
• Peso molecular: 265.18
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825916
• NACRES: NA.77

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D +20 to +30°, c = 1 in methanol
• color: white to beige
• solubility: H₂O: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CC1=C(OC[C@@H]2CCCN2)C=CC=N1.[H]Cl.[H]Cl
• InChI: 1S/C11H16N2O.2ClH/c1-9-11(5-3-6-12-9)14-8-10-4-2-7-13-10;;/h3,5-6,10,13H,2,4,7-8H2,1H3;2*1H/t10-;;/m0../s1
• InChI key: UGVSESCRKJTJAK-XRIOVQLTSA-N

Descripción

Biochem/physiol Actions

ABT-089 (Pozanicline) is a subtype-selective neuronal nicotinic receptor partial agonist binding primarily to the α4β2 and also α6β2 subtypes. It has been investigated for alleviating symptoms of nicotine withdrawal including cognitive deficits and anxiety.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable