SML0983

5F-203

≥98% (HPLC)

• Sinónimos: 4-(5-Fluoro-2-benzothiazolyl)-2-methyl-benzenamine, 5F203, NSC-703786
• Fórmula empírica (notación de Hill): C₁₄H₁₁FN₂S
• Número de CAS: 260443-89-8
• Peso molecular: 258.31
• Código UNSPSC: 12352200
• NACRES: NA.77

Propiedades

• Ensayo: ≥98% (HPLC)
• Formulario: powder
• color: white to beige
• solubilidad: DMSO: 20 mg/mL, clear
• temp. de almacenamiento: 2-8°C
• cadena SMILES: Fc1cc2nc([s]c2cc1)c3cc(c(cc3)N)C
• InChI: 1S/C14H11FN2S/c1-8-6-9(2-4-11(8)16)14-17-12-7-10(15)3-5-13(12)18-14/h2-7H,16H2,1H3
• Clave InChI: IFWLHIIUGSEKKE-UHFFFAOYSA-N

Descripción

Acciones bioquímicas o fisiológicas

5F-203 is a cytotoxic molecule that forms DNA adducts that lead to cell death.

5F-203 is a cytotoxic molecule that forms DNA adducts that lead to cell death. 5F-203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. Treatment of cells with 5F-203 also leads to elevation of reactive oxygen species and activation of p38, JNK and ERK.

Características y beneficios

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Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Consejos de prudencia: P264 - P270 - P301 + P312 - P501
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable