SML0733

Cilomilast

≥95% (HPLC)

• Sinónimos: SB 207499, SB-207499, cis-4-Cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid
• Fórmula empírica (notación de Hill): C₂₀H₂₅NO₄
• Número CAS: 153259-65-5
• Peso molecular: 343.42
• UNSPSC Code: 41106305
• NACRES: NA.77
• Assay: ≥95% (HPLC)
• Form: powder

Propiedades

• assay: ≥95% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 15 mg/mL, clear
• storage temp.: −20°C
• SMILES string: N#CC3(CCC(CC3)C(=O)O)c1cc(c(cc1)OC)OC2CCCC2
• InChI: 1S/C20H25NO4/c1-24-17-7-6-15(12-18(17)25-16-4-2-3-5-16)20(13-21)10-8-14(9-11-20)19(22)23/h6-7,12,14,16H,2-5,8-11H2,1H3,(H,22,23)
• InChI key: CFBUZOUXXHZCFB-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Cilomilast (SB-207499) is a potent, selective and orally available PDE4 inhibitor that exhibits anti-inflamatory and anti-asthmatic activity.

Cilomilast (SB-207499) is a potent, selective and orally available PDE4 inhibitor.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable