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SML0054

Sigma-Aldrich

Schizandrin

≥98% (HPLC)

Sinónimos:

(+)-Schizandrin, Schisandrin, Schisandrine, Wuweizi alcohol A, Wuweizichun A

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About This Item

Fórmula empírica (notación de Hill):
C24H32O7
Número de CAS:
7432-28-2
Peso molecular:
432.51
MDL number:
MFCD00905761
UNSPSC Code:
12352200
PubChem Substance ID:
329825121
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D 75 to 95°, c = 1 in methanol

color

white to beige

solubility

DMSO: ≥13 mg/mL

storage temp.

room temp

SMILES string

COc1cc2C[C@H](C)[C@@](C)(O)Cc3cc(OC)c(OC)c(OC)c3-c2c(OC)c1OC

InChI

1S/C24H32O7/c1-13-9-14-10-16(26-3)20(28-5)22(30-7)18(14)19-15(12-24(13,2)25)11-17(27-4)21(29-6)23(19)31-8/h10-11,13,25H,9,12H2,1-8H3/t13-,24-/m0/s1

InChI key

YEFOAORQXAOVJQ-RZFZLAGVSA-N

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Application

Schizandrin may be used in oxidative stress-related cell signaling studies.

Biochem/physiol Actions

Schizandrin is a natural product with several biological properties involved with antioxidant and anti-inflammatory activities. It reduces the formation of ROS, inhibits the mitochondrial pathway of the apoptotic process and oxidative stress. Schizandrin has been reported to have hepatoprotective, antitumor, antiviral, and antiamnesic effects, and has neuroprotective activity against glutamate induced neurotoxicity.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Shih-Hung Yang et al.
Journal of the science of food and agriculture, 91(4), 694-702 (2011-02-09)
Schisandra chinensis, commonly used in Asia for tea material and traditional Chinese medicine, is presumed to enhance mental and intellectual functions. In this study, the effects and signalling mechanisms of a purified compound schisandrin, one of the lignan of Schisandra
Bing Shao et al.
Drug development and industrial pharmacy, 36(11), 1356-1363 (2010-09-21)
Wurenchun is the alcohol extract from Fructus Schisandrae Chinensis, which has good efficiency in lowering abnormal serum glutamic pyruvic transaminase (SGPT) level of patients suffering from acute or chronic hepatitis. The main purpose of this work is to prepare self-emulsifying
Jia-Ming Yang et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(13), 1153-1160 (2011-07-19)
In this study, the herbal extracts of Schisandra chinensis were demonstrated to inhibit the contractions induced by acetylcholine (ACh) and serotonin (5-HT) in guinea pig ileum, and the 95% ethanol extract was more effective than the aqueous extract. Analysis with
Si-Yuan Pan et al.
Lipids in health and disease, 11, 120-120 (2012-09-20)
Schisandra, a globally distributed plant, has been widely applied to health care products. Here, we investigated the effects of dietary intake of Fructus Schisandrae chinensis (FSC), both aqueous and ethanolic extracts (AqFSC, EtFSC), on serum/hepatic lipid contents in normal diet
Sun Young Park et al.
Immunology letters, 139(1-2), 93-101 (2011-06-08)
The lipopolysaccharide (LPS) of Porphyromonas gingivalis is thought to induce periodontitis. In this study, we isolated Schisandrin from the dried fruits of Schisandra chinensis and examined the anti-inflammatory effect of Schisandrin in macrophages stimulated with LPS from P. gingivalis. First
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