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SCP0139

Sigma-Aldrich

Caspase 8 Substrate, fluorogenic

≥95% (HPLC), lyophilized

Sinónimos:

Ac-VETD-AMC

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About This Item

Fórmula empírica (notación de Hill):
C30H39N5O12
Peso molecular:
661.66
UNSPSC Code:
12352202
NACRES:
NA.32

product name

Caspase 8 Substrate, fluorogenic,

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥67%

storage condition

protect from light

storage temp.

−20°C

Gene Information

human ... CASP8(841)

Amino Acid Sequence

Ac-Val-Glu-Thr-Asp-AMC

Application

Fluorogenic caspase 8 substrate has been used to measure caspase 8 activity in Jurkat cell lysates.

Biochem/physiol Actions

The peptide Ac-Val-Glu-Thr-Asp-AMC, or Ac-VETD-AMC, is a fluorogenic, modified peptide substrate for caspase 8.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Ali, S.M., et al.
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WuyuanLu Erikde Leeuw
Febs Letters, 558(10) (2014)
T L Yue et al.
The Journal of biological chemistry, 274(3), 1479-1486 (1999-01-09)
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Mikhail G Akimov et al.
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Cholines acylated with unsaturated fatty acids are a recently discovered family of endogenous lipids. However, the data on the biological activity of acylcholines remain very limited. We hypothesized that acylcholines containing residues of arachidonic (AA-CHOL), oleic (Ol-CHOL), linoleic (Ln-CHOL), and
Natalia M Gretskaya et al.
European journal of pharmacology, 883, 173346-173346 (2020-07-14)
Glioblastoma (GBM) is an aggressive and lethal form of brain cancer with a high invasion capacity and a lack of effective chemotherapeutics. Retinoid bexarotene (BXR) inhibits the neurospheroidal colony formation and migration of primary glioblastoma cells but has side effects.

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