The details of the manufacturing processing cannot be shared, for proprietary reasons, but the product is not sterile filtered. It is is packaged under aseptic conditions.
SBR00068
Streptomycin Ready Made Solution
100 mg/mL in water
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About This Item
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form
liquid
Quality Level
specific activity
(Antibacterial)
concentration
100 mg/mL in water
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
mode of action
protein synthesis | interferes
storage temp.
−20°C
SMILES string
[S](=O)(=O)(O)O.[S](=O)(=O)(O)O.[S](=O)(=O)(O)O.N([C@@H]4[C@@H](O[C@H]([C@@H]([C@H]4O)O)CO)O[C@H]5[C@@H](O[C@H]([C@]5(O)C=O)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H]([C@@H]6O)O)N=C(N)N)O)N=C(N)N)C.N([C@@H]1[C@@H](O[C@H]([C@@H]([C@H]1O)O)CO)O[C@H]2[C@@H](O[C@H]([
InChI
1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7-,8+,9-,10-,11-
InChI key
QTENRWWVYAAPBI-YZTFXSNBSA-N
General description
Chemical structure: aminoglycoside
Application
Streptomycin is used to study mechanisms of streptomycin resistance and is often used together with penicillin and other agents to inhibit bacterial contamination in cell culture applications. It is recommended for use in molecular biology applications at 25-50 μg/mL, in cell culture applications at 100 mg/L and in embryo culture at 50 mg/L.
Biochem/physiol Actions
Mode of Action: Streptomycin acts by inhibiting prokaryote protein synthesis by binding to the S12 protein of the 30S ribosomal subunit, thus preventing the transition from imitation complex to chain-elongating ribosome. This causes miscoding or inhibits initiation.
Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.
Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.
Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.
Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.
Storage and Stability
- Streptomycin ready made solution contains 100 mg/mL streptomycin sulfate in water.
- Streptomycin: sulfate salt ratio is 1:1.5.
- The product is packed under aseptic conditions.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
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Streptomycin ready made solution 100mg/ml cat # SBR00068 : is the solution filtered at the end of the preparation? Thank you
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