SBPVR4

SB PREDIVEZ^™ Reagent Kit for BCRP

• UNSPSC Code: 12161503
• Storage temp.: −70°C
• Shipped in: dry ice

Propiedades

• recombinant: expressed in human cells
• form: liquid
• shipped in: dry ice
• storage temp.: −70°C

Descripción

General description

SOLVO Biotechnology offers ready-to-use assay kits for efflux and uptake transporters. SOLVO′s PREDIVEZ Vesicular Transport Assay Kits are suitable for efflux transporter inhibition studies. The kits are designed to test the inhibitory effect of one or more test compounds on the vesicular transport of a probe substrate. In most cases a fluorescent probe substrate is included. Kits contain all reagents and solutions necessary to conduct the drug-transporter interaction assay of need.

Application

The PREDIVEZ Vesicular Transport Kit is a simple and powerful tool to investigate drug transporter interactions. It provides information on any interaction between the ABC transporter and the drug candidate that would affect the transport of the fluorescent or radiolabeled or cold.

PREDIVEZ vesicular transport kits contains buffers, probe substrate, and reference inhibitors needed to run vesicular transport assays (sufficient for 300 wells/kit –equivalent to existing 9-cpd PV kits). Assay protocol, calculation template, and example data file available on SOLVO website.

Transport membranes and control membranes are sold separately. This PREDIVEZ vesicular transport kit requires the transporter membranes and corresponding control membrane below:

SSB-BCRP-M-VT BCRP human membrane vesicles part number SBVT09-1EA and corresponding control membrane SB-M-CTRL part number SBCT02-1EA

SB-BCRP-HEK293-VT BCRP human membrane vesicles part number SBVT17-1EA and corresponding control membrane SB-HEK293-Mock-CTRL part number SBCT06-1EA

PREDIVEZ^™ vesicular transport reagent Kit may be used for assessing human ATP binding cassette subfamily B member 1 (ABCB1) function and multidrug resistance-associated protein 2 (MRP2) efflux transporter function.

Legal Information

PREDIVEZ is a trademark of Solvo Biotechnology

Información de seguridad

• Pictogramas: GHS05,GHS07
• Palabra de advertencia: Warning
• Códigos de peligro: H290,H317
• Indicaciones de precaución: P234 - P261 - P272 - P280 - P302 + P352 - P333 + P313
• Hazard Classifications: Met. Corr. 1 - Skin Sens. 1
• Punto de inflamación (°F): 188.6 °F
• Punto de inflamación (°C): 87 °C
• Clase de almacenamiento: 10 - Combustible liquids