SAB4702019

Monoclonal Anti-CD82 purified low endotoxin produced in mouse

• Sinónimos: 4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27
• Código UNSPSC: 12352203

Propiedades

• conjugado: unconjugated
• Nivel de calidad: 100
• tipo de anticuerpo: primary antibodies
• clon: C33, monoclonal
• Formulario: buffered aqueous solution
• reactividad de especies: human
• concentración: 1 mg/ml
• técnicas: FUNC: suitable; flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• isotipo: IgG2a
• Nº de acceso UniProt: P27701
• temp. de almacenamiento: 2-8°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CD82(3732)

Descripción

Descripción general

CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.

Especificidad

The mouse monoclonal antibody C33 recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.

Inmunógeno

C91/PL (human HTLV-1+ T cell line)

Forma física

Phosphate buffered saline (PBS), pH 7.4

Nota de preparación

Purified by protein-A affinity chromatography.

Almacenamiento y estabilidad

Store at 2-8°C. Do not freeze.

Otras notas

The antibody solution should be gently mixed before use.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1