SAB4700092
Monoclonal Anti-CD9 antibody produced in mouse
clone MEM-61, purified immunoglobulin, buffered aqueous solution
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Productos recomendados
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
MEM-61, monoclonal
form
buffered aqueous solution
species reactivity
human
concentration
1 mg/mL
technique(s)
flow cytometry: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... CD9(928)
Categorías relacionadas
General description
CD9 (cluster of differentiation 9) is a human cell surface antigen. CD9 gene contains 8 exons extending over a length of 20kb on genomic DNA.The gene is mapped to human chromosome 2q12-pter. The encoded protein has a molecular weight of 24kDa and is expressed mainly on B-lineage-derived acute lymphoblastic leukemia cells and developing B lymphocytes.The protein is also present in blood platelets, neuroblastoma cell lines, normal and transformed epithelia, peripheral glia and neurons. CD9 antigen belongs to the transmembrane 4 superfamily (TM4SF) and is characterized with two external loops and four hydrophobic domains of membrane-spanning length.
Immunogen
Pre-B cell line NALM-6
Application
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Biochem/physiol Actions
Members of transmembrane 4 superfamily (TM4SF) including CD9 (cluster of differentiation 9) plays a vital role in cell proliferation, activation, motility and tumor cell metastasis. CD9 facilitates platelet activation and aggregation. The encoded protein also plays a major role in the amplification of a motorgenic signal in B cells includingβ1 integrins and the activation of protein tyrosine kinases. CD9 interacts with GM3 and downregulates tumor cell motility. CD9 and CD81 stimulate muscle cell fusion and aids in myotube maintenance.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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The Journal of Biological Chemistry, 270, 24092-24099 (1995)
Platelet activation by immobilized monoclonal antibody: evidence for a CD9 proximal signal.
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