SAB4503879

Anti-phospho-HSL (pSer⁵⁵²) antibody produced in rabbit

affinity isolated antibody

• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 116 kDa
• species reactivity: mouse, rat, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:5000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: Q05469
• UniProt accession no.: Q05469
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer552)
• Gene Information: human ... LIPE(3991)

Descripción

General description

Hormone sensitive lipase (HSL) is coded by LIPE (lipase E) gene. It is an intracellular lipase with substrates as triglycerides, diglycerides, monoglycerides, cholesterol esters and retinyl esters. HSL is mapped to human chromosome 19q13.

Immunogen

The antiserum was produced against synthesized peptide derived from human HSL around the phosphorylation site of Ser552.

Immunogen Range: 518-567

Application

Anti-HSL antibody has been used in western blotting.

Biochem/physiol Actions

Hormone sensitive lipase (HSL) plays an important role in lipolysis. Lack of HSL results in histologic abnormalities in white adipose tissue and an increase in macrophage infiltration.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable