SAB4502387

Anti-PKG2 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: CGK 2, Type II cGMP-dependent protein kinase, cGKII
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 87 kDa
• reactividad de especies: mouse, rat, human
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:40000; western blot: 1:500-1:1000
• Nº de acceso NCBI: Q13237
• Nº de acceso UniProt: Q13237
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... PRKG2(5593)

Descripción

Descripción general

Anti-PKG2 Antibody detects endogenous levels of total PKG2 protein.

Type II cGMP-dependent protein kinase (PRKG2) is encoded by the gene mapped to human chromosome 4q13.1–q21.1.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human PKG2.

Immunogen Range: 92-141

Acciones bioquímicas o fisiológicas

Type II cGMP-dependent protein kinase (PRKG2) is implicated in the regulation of intestinal fluid balance in humans. The encoded protein plays an essential role in proliferative to hypertrophic transition of growth plate chondrocytes during endochondral ossification. Loss of PRKG2 function is associated with the development of renal cysts, intellectual disability and speech defect. In rodent and bovine models, deletion of the gene leads to dwarfism.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable