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Merck
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SAB4502050

Sigma-Aldrich

Anti-OR1D2 antibody produced in rabbit

affinity isolated antibody

Sinónimos:

OR17-4, Olfactory receptor 17-4, Olfactory receptor 1D2, Olfactory receptor OR17-6, Olfactory receptor-like protein HGMP07E

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100 μG
MXP 7,922.00

MXP 7,922.00

Fecha estimada de envío24 de abril de 2025

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100 μG
MXP 7,922.00

About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

MXP 7,922.00

Fecha estimada de envío24 de abril de 2025

origen biológico

rabbit

Nivel de calidad

100

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

Formulario

buffered aqueous solution

mol peso

antigen 35 kDa

reactividad de especies

human

concentración

~1 mg/mL

técnicas

ELISA: 1:20000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000

Nº de acceso NCBI

P34982

Nº de acceso UniProt

P34982

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... OR1D2(4991)

Descripción general

Anti-OR1D2 antibody detects endogenous levels of total OR1D2 protein.
The OR1D2 (olfactory receptor family 1 subfamily D member 2) gene is located on human chromosome 17p13.3. The gene is considered as the first olfactory receptor expressed in the nose. It is also found to be expressed in spermatozoa. The encoded protein is a member of G protein-coupled receptor superfamily and exists as a homo-oligomer.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human OR1D2.

Immunogen Range: 201-250

Acciones bioquímicas o fisiológicas

The protein encoded by OR1D2 (olfactory receptor family 1 subfamily D member 2) gene takes part in the process of fertilization by mediating the communication between the sperm and egg via chemotaxis. Sperm expressing OR1D2 is known to migrate toward odorant ligands such as lilial, floralozone and bourgeonal.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

nwg

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
61516

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G Ottaviano et al.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 270(12), 3079-3086 (2013-03-26)
Olfactory receptor (OR) expression is also present in the sperm cells and could mediate sperm chemotaxis. OR1D2 was the first OR expressed in the testis demonstrated to be involved in chemotaxis and to be expressed also in the nose with
Marc Spehr et al.
Science (New York, N.Y.), 299(5615), 2054-2058 (2003-03-29)
Although it has been known for some time that olfactory receptors (ORs) reside in spermatozoa, the function of these ORs is unknown. Here, we identified, cloned, and functionally expressed a previously undescribed human testicular OR, hOR17-4. With the use of
Brian L Cook et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(29), 11925-11930 (2009-07-08)
Although understanding of the olfactory system has progressed at the level of downstream receptor signaling and the wiring of olfactory neurons, the system remains poorly understood at the molecular level of the receptors and their interaction with and recognition of
Fallou Wade et al.
The Journal of biological chemistry, 286(17), 15252-15259 (2011-04-02)
G-protein-coupled receptor homo-oligomerization has been increasingly reported. However, little is known regarding the relationship between activation of the receptor and its association/conformational states. The mammalian olfactory receptors (ORs) belong to the G protein-coupled receptor superfamily. In this study, the homo-oligomerization
A partial deletion of the aspartoacylase gene is the cause of Canavan disease in a family from Mexico.
F E Tahmaz et al.
Journal of medical genetics, 38(3), E9-E9 (2001-03-10)

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