SAB4300522

Anti-DOK2 (Ab-299) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-docking protein 2, 56kDa antibody produced in rabbit, Anti-p56DOK antibody produced in rabbit, Anti-p56dok-2 antibody produced in rabbit
• Número MDL: MFCD03455698
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: ~56 kDa
• reactividad de especies: human
• concentración: 1 mg/mL
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• isotipo: IgG
• secuencia del inmunógeno: (G-E-Y-A-V)
• Nº de acceso NCBI: NP_003965.2
• Nº de acceso UniProt: O60496
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... DOK2(9046)

Descripción

Inmunógeno

Peptide sequence around aa. 297-301 (G-E-Y-A-V), according to the protein DOK2.

Características y beneficios

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Descripción de destino

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation.

Forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable