SAB4200464

Anti-WDR37 antibody, Mouse monoclonal

clone WDR37-9, purified from hybridoma cell culture

• Sinónimos: Monoclonal Anti-RP11-529L18.2, Monoclonal Anti-WD repeat domain 37, Monoclonal Anti-WDR37 antibody produced in mouse
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• conjugado: unconjugated
• forma del anticuerpo: purified from hybridoma cell culture
• tipo de anticuerpo: primary antibodies
• clon: WDR37-9, monoclonal
• Formulario: buffered aqueous solution
• mol peso: antigen ~55 kDa
• reactividad de especies: human, mouse
• concentración: ~1.0 mg/mL
• técnicas: indirect immunofluorescence: 2.5-5.0 μg/mL using A431 cells.; western blot: 3.0-6.0 μg/mL using U87 total cell extracts.
• isotipo: IgG1
• Nº de acceso UniProt: Q9Y2I8
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... WDR37(22884) ; mouse ... Wdr37(207615)

Descripción

Descripción general

WDR37 (WD repeat- containing protein 37), is a 494 amino acid protein that contains seven WD-repeats. WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. The gene encoding WDR37 maps to human chromosome 10q15.3. WDR37 gene is located in loci responsible for renal function and chronic kidney disease (CKD).

Inmunógeno

synthetic peptide corresponding to a sequence at the N-terminus of human WDR37, conjugated to KLH. The isotype is determined by ELISA using Mouse Monoclonal Antibody Isotyping Reagents (Sigma ISO-2).

Aplicación

Monoclonal Anti-WDR37 antibody produced in mouse has been used in:

• immunofluorescence
• immunoblotting
• immunohistochemistry
• immunocytochemistry

Acciones bioquímicas o fisiológicas

Proteins containing WD-repeats participate in a wide range of cellular functions, such as chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking.

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable