Toll-like receptor 4 (TLR4) belongs to the interleukin-1 receptor (IL-1R) family. It is highly polymorphic and is located on human chromosome 9q33.1.
Inmunógeno
Antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TLR4.
Acciones bioquímicas o fisiológicas
Toll-like receptor 4 (TLR4) acts as the receptor for LPS (lipopolysaccharides ), a gram-negative bacterial cell wall component. Mutations in TLR4 affects mRNA and protein expression in colorectal cancer.
Características y beneficios
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Ligadura / enlace
The action of this antibody can be blocked using blocking peptide SBP3500765.
Forma física
Supplied at 1 mg/mL in PBS with 0.02% sodium azide.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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International journal of biological sciences, 16(9), 1481-1494 (2020-04-01)
Inflammation and apoptosis are considered as two major pathological causes of human sarcopenia. The current understanding based on different models recognizes that apoptosis does not trigger inflammation, while emerging evidence indicates that inflammation can induce apoptosis. Here, we provide solid
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