SAB2501804

Anti-CCL20 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Sinónimos: CKb4, LARC, MIP-3a, chemokine (C-C motif) ligand 20
• Código UNSPSC: 12352203

Propiedades

• origen biológico: goat
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• reactividad de especies: human, bovine, pig
• técnicas: immunohistochemistry: suitable; indirect ELISA: suitable
• Nº de acceso UniProt: P78556
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CCL20(6364)

Descripción

Descripción general

Chemokine ligand 20 (CCL20) is also called as liver and activation-regulated chemokine, macrophage inflammatory protein-3α (MIP-3α) or exodus-1. It is a cysteine−cysteine chemokine, that is located on human chromosome 2q36. It is expressed at high levels in serum or IgA1 and HMC incubation system. The CCL20 promoter region consists of a transcription start site, a nuclear factor (NF)-κB binding site, a CCAAT/enhancer-binding proteins binding site, an activator protein-1 binding sites and a specificity protein 1 (Sp1)-binding site.

Inmunógeno

Peptide with sequence CLGYTDRILHPK, from the internal region of the protein sequence according toNP_004582.1; NP_001123518.1

Acciones bioquímicas o fisiológicas

Chemokine ligand 20 (CCL20) is chemotactic for immature dendritic cells, effector or memory CD4⁺T lymphocytes and B lymphocytes. CCR6 (C-C chemokine receptor type 6), the receptor of CCL20, plays a vital role in the progression of several diseases, such as tumors, rheumatoid arthritis, pneumococcal meningitis and human renal inflammation.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable