S8647

Sulfacetamide sodium salt monohydrate

• Fórmula empírica (notación de Hill): C₈H₉N₂NaO₃S · H₂O
• Número CAS: 6209-17-2
• Peso molecular: 254.24
• NACRES: NA.85
• PubChem Substance ID: 24899806
• UNSPSC Code: 51102829
• MDL number: MFCD00149555

Propiedades

• form: powder
• color: white to off-white
• solubility: H₂O: soluble 50 mg/mL
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria, mycoplasma
• mode of action: DNA synthesis | interferes, enzyme | inhibits
• SMILES string: NC1=CC=C(S(N([Na])C(C)=O)(=O)=O)C=C1.O
• InChI: 1S/C8H10N2O3S.Na.H2O/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8;;/h2-5H,9H2,1H3,(H,10,11);;1H2/q;+1;/p-1
• InChI key: IHCDKJZZFOUARO-UHFFFAOYSA-M

Descripción

General description

Chemical structure: sulfonamide

Biochem/physiol Actions

Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Packaging

100G

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Storage class (TRGS 510): Non Combustible Solids

Información de seguridad

• Clase de almacenamiento: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)