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Merck

S5799

Sigma-Aldrich

Suberic acid bis(3-sulfo-N-hydroxysuccinimide ester) sodium salt

≥95% (H-NMR), powder

Sinónimos:

BS3, Bis(sulfosuccinimidyl) suberate sodium salt

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25 MG
MXP 3,112.00
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MXP 8,462.00

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25 MG
MXP 3,112.00
100 MG
MXP 8,462.00

About This Item

Fórmula empírica (notación de Hill):
C16H18N2Na2O14S2
Número de CAS:
Peso molecular:
572.43
Número MDL:
Código UNSPSC:
12352106
ID de la sustancia en PubChem:
NACRES:
NA.22

MXP 3,112.00


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grado

for analytical purposes

Nivel de calidad

Ensayo

≥95% (H-NMR)

Formulario

powder

idoneidad de la reacción

reagent type: cross-linking reagent

solubilidad

H2O: 10 mg/mL
DMF: soluble

temp. de almacenamiento

−20°C

cadena SMILES

[Na+].[Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)CCCCCCC(=O)ON2C(=O)CC(C2=O)S([O-])(=O)=O)C1=O

InChI

1S/C16H20N2O14S2.2Na/c19-11-7-9(33(25,26)27)15(23)17(11)31-13(21)5-3-1-2-4-6-14(22)32-18-12(20)8-10(16(18)24)34(28,29)30;;/h9-10H,1-8H2,(H,25,26,27)(H,28,29,30);;/q;2*+1/p-2

Clave InChI

MGJYOHMBGJPESL-UHFFFAOYSA-L

Descripción general

Suberic acid bis(3-sulfo-N-hydroxysuccinimide ester) sodium salt (BS3) is a water soluble, homobifunctional cross-linking reagent with amine reactivity. It is typically coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). It incorporates 8-atom linker.[1]

Aplicación

Suberic acid bis(3-sulfo-N-hydroxysuccinimide ester) sodium salt (BS3) is useful for the preparation of protein-protein, receptor-ligand and hapten carrier molecule conjugates.[2][3][4]

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Modelling the structure of latexin-carboxypeptidase A complex based on chemical cross-linking and molecular docking.
Mouradov D
Protein engineering, design & selection : PEDS, 19, 9-16 (2006)
Modified apolipoprotein (apo) A-I by artificial sweetener causes severe premature cellular senescence and atherosclerosis with impairment of functional and structural properties of apoA-I in lipid-free and lipid-bound state.
Jang W
Molecular Cell, 31, 461-461 (2011)
Huawen Lin et al.
PLoS genetics, 9(9), e1003841-e1003841 (2013-10-03)
Whole genome sequencing is a powerful tool in the discovery of single nucleotide polymorphisms (SNPs) and small insertions/deletions (indels) among mutant strains, which simplifies forward genetics approaches. However, identification of the causative mutation among a large number of non-causative SNPs
Hermanson GT
Bioconjugate Techniques (2013)
Bovine apolipoprotein (apo)A-I displays more enhanced antioxidant and anti-atherosclerotic activity in lipid-free and lipid-bound states than human and porcine apoA-I.
Kim SM
International Journal of Molecular Medicine, 32, 843-843 (2013)

Questions

1–3 of 3 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. What is reconstituent procedure?

    1 answer
    1. There is no reconstitution protocol offered with this material. This product can be reconstituted in water at 10 mg/mL. Once reconstituted, solutions can be stored at 0 - 4°C for the short term. Solution stability studies have not been performed.

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