S0575

Anti-SET (56-70) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Sinónimos: Anti-2PP2A, Anti-I2PP2A, Anti-IGAAD, Anti-IPP2A2, Anti-PHAPII, Anti-SET Isoform 2 of Protein SET, Anti-TAF-I, Anti-TAF-Iβ
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: IgG fraction of antiserum
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen ~32 kDa
• reactividad de especies: human
• técnicas: western blot: 1:500-1:2,000
• Nº de acceso UniProt: Q01105
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... SET(6418)

Descripción

Descripción general

SET (SET nuclear oncogene) is an oncoprotein. It is also termed as I2PP2A (protein phosphatase type 2A inhibitor II)/TAF-1β. It is located on human chromosome 9q34.11. SET belongs to the inhibitor of histone acetyltransferase (INHAT) complex, that blocks histone acetylation.

Inmunógeno

synthetic peptide corresponding to amino acids 56-70 of human SET

Aplicación

Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

Acciones bioquímicas o fisiológicas

SET (SET nuclear oncogene) oncoprotein participates in several aspects related to chromatin structure. It is considered as a histone chaperone, which is essential for chromatin transcription and a vital modulator of chromosome condensation.

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)