RAB1476

Human GAPHD ELISA

for serum, plasma and cell culture supernatants

• Código UNSPSC: 41116158
• NACRES: NA.32

Propiedades

• reactividad de especies: human
• envase: kit of 96 wells (12 strips x 8 wells)
• técnicas: ELISA: suitable
• entrada: sample type cell culture supernatant(s); sample type serum; sample type plasma
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 0.82 ng/mL; standard curve range: 0.819-200 ng/mL
• método de detección: colorimetric
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... GAPDH(2597)

Descripción

Descripción general

The GAPHD (glyceraldehyde-3-phosphate dehydrogenase) gene is mapped to human chromosome 12p13.31.[1] GAPHD encodes a multifunctional protein which is a glycolytic enzyme.[2][3]

This ELISA antibody pair detects human GAPHD. Other species not yet determined.

Aplicación

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Acciones bioquímicas o fisiológicas

GAPHD (glyceraldehyde-3-phosphate dehydrogenase) is associated with the progression of Huntington′s disease by increasing cytotoxicity.[4] Gaphd is often referred to as glycolytic enzyme and catalyzes the sixth step in glycolysis.[3][1] The Gaphd enzyme possess uracil-DNA glycosylase activity.[3] The enzyme regulates transcription, posttranscriptional gene expression, intracellular membrane trafficking and apoptosis.[2]

Otras notas

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Información de seguridad

• Pictogramas: GHS05
• Palabra de señalización: Warning
• Frases de peligro: H290
• Consejos de prudencia: P234 - P390
• Clasificaciones de peligro: Met. Corr. 1
• Código de clase de almacenamiento: 8A - Combustible corrosive hazardous materials
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable