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RAB0606

Sigma-Aldrich

Human ANGPTL3 / Angiopoietin-related Protein 3 ELISA Kit

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8.2 pg/mL
standard curve range: 8.19-2000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... ANGPTL3(27329)

General description

Angiopoietin-related protein 3 (ANGPTL3) is a member of the ANGPTL family and is expressed in the liver. The ANGPTL3 gene is mapped on the human chromosome at 1p31.3. Mutations in the ANGPTL3 gene lead to familial combined hypolipidemia, a Mendelian condition that is indicated by lower levels of triglycerides, high-density lipoprotein (HDL), and low-density lipoprotein cholesterol. The ANGPTL3 enzyme-linked immunosorbent assay (ELISA) kit provides for the quantitative measurement of angiopoietin-related protein 3 in cell culture supernatants, plasma, and serum.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Junpeng Ma et al.
Frontiers in oncology, 10, 1382-1382 (2020-09-15)
Meningiomas, as the most common primary tumor of the central nervous system, are known to harbor genomic aberrations that associate with clinical phenotypes. Here we performed genome-wide genotyping for cranial meningiomas in 383 Chinese patients and identified 9,821 copy-number variations
Maria Fernanda Garcés et al.
Scientific reports, 10(1), 21118-21118 (2020-12-05)
This study aimed to determine ANGPTL3 serum levels in healthy young lean and obese non-diabetic men during an oral glucose tolerance test (OGTT) and correlate them with anthropometric, biochemical and hormonal parameters. A case-control study was carried out and 30
Fabiana Quagliarini et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(48), 19751-19756 (2012-11-15)
Angiopoietin-like proteins (ANGPTLs) play major roles in the trafficking and metabolism of lipids. Inactivation of ANGPTL3, a gene located in an intron of DOCK7, results in very low levels of LDL-cholesterol (C), HDL-C and triglyceride (TAG). We identified another ANGPTL
Nathan O Stitziel et al.
Journal of the American College of Cardiology, 69(16), 2054-2063 (2017-04-08)
Familial combined hypolipidemia, a Mendelian condition characterized by substantial reductions in all 3 major lipid fractions, is caused by mutations that inactivate the gene angiopoietin-like 3 (ANGPTL3). Whether ANGPTL3 deficiency reduces risk of coronary artery disease (CAD) is unknown. The study
Andrew A Butler et al.
Journal of lipid research, 61(3), 376-386 (2020-01-11)
Angiopoietin-like protein 3 (ANGPTL3) inhibits lipid clearance and is a promising target for managing cardiovascular disease. Here we investigated the effects of a high-sugar (high-fructose) diet on circulating ANGPTL3 concentrations in rhesus macaques. Plasma ANGPTL3 concentrations increased ∼30% to 40%
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