PRS3953

Anti-RIG-1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-DEAD (Asp-Glu-Ala-Asp) box polypeptide 58, Anti-Dead box protein 58, Anti-Retinoic acid inducible gene 1 protein, Anti-ddx58
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• reactividad de especies: mouse, rat, human
• técnicas: immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• Nº de acceso UniProt: O95786
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... DDX58(23586)

Descripción

Descripción general

RIG-1 (retinoic acid-inducible gene I) is a cytoplasmic viral RNA receptor, that is also known as DDX58 (DExD/H-box helicase 58). It belongs to RIG-I-like receptor (RLR) family. It has 2 N-terminal caspase recruitment domains (CARDs), a central RNA helicase domain, and a C-terminal RNA-binding domain. It is located on chromosome 9p21.1.

Inmunógeno

human GST-tagged RIG-1 protein.

Acciones bioquímicas o fisiológicas

DDX58 (DExD/H-box helicase 58) mutations leads to atypical singleton-merten syndrome. It participates in immune regulation and activation of astrocyte.

Forma física

Solution in phosphate buffered saline containing 0.02% sodium azide

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable