P9511

3-sn-Phosphatidic acid sodium salt from egg yolk lecithin

≥98%

• Sinónimos: 1,2-Diacyl-sn-glycero-3-phosphate sodium salt, L-α-Phosphatidic acid sodium salt, PA
• MDL number: MFCD00063023
• UNSPSC Code: 12352106
• PubChem Substance ID: 329820351
• NACRES: NA.77

Propiedades

• Quality Level: 200
• assay: ≥98%
• form: powder
• storage temp.: −20°C
• SMILES string: [Na+].[Na+].OC[C@@H](O)COP([O-])([O-])=O
• InChI: 1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;/q;2*+1/p-2/t3-;;/m1../s1
• InChI key: GEKBIENFFVFKRG-HWYNEVGZSA-L

Descripción

General description

Phosphatidic acid is obtained from phosphatidylcholine with the help of phospholipase D.[1]

Application

3-sn-Phosphatidic acid sodium salt from egg yolk lecithin

• in the reaction mixture for CDS (cytidine triphosphate:phosphatidate cytidyltransferase) assay and reference lipid for thin layer chromatography (TLC)[2]
• as a standard to compare the generated radiolabeled phosphatidic acid (PA)[3]
• to examine its effects on At-Rac2–associated kinase activity[4]

Biochem/physiol Actions

Phosphatidic acid might serve as a modulator of phagocyte respiratory burst. It also acts as a precursor of diacylglycerol, phosphatidic acid and lysophosphatidic acid.[1]

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphodiesterases, Phosphoinositide Kinases and Phosphoprotein Phosphatases (Serine/Threonine) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

Prepared from L-α-phosphatidylcholine by hydrolysis with cabbage phospholipase D.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)