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P6902

Sigma-Aldrich

Pheniramine maleate salt

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About This Item

Fórmula empírica (notación de Hill):
C16H20N2 · C4H4O4
Número de CAS:
132-20-7
Peso molecular:
356.42
EC Number:
205-051-4
MDL number:
MFCD00079250
UNSPSC Code:
12352116
PubChem Substance ID:
24277769
NACRES:
NA.77

form

powder

SMILES string

OC(=O)\C=C/C(O)=O.CN(C)CCC(c1ccccc1)c2ccccn2

InChI

1S/C16H20N2.C4H4O4/c1-18(2)13-11-15(14-8-4-3-5-9-14)16-10-6-7-12-17-16;5-3(6)1-2-4(7)8/h3-10,12,15H,11,13H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

SSOXZAQUVINQSA-BTJKTKAUSA-N

Gene Information

human ... HRH1(3269)

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Biochem/physiol Actions

Pheniramine maleate is a H1 histamine receptor antagonist. It is an alkylamine derivative. Structurally, pheniramine contains a chiral carbon atom with a hydrogen atom. Other substituents include the pyridyl, alkylamine and phenyl groups. It is used as an antiallergic drug for treating the common cold, respiratory allergies, urticaria, and systematic allergic reactions.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

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Ching-Hsia Hung et al.
European journal of pharmacology, 673(1-3), 20-24 (2011-11-03)
The aim of this study was to evaluate the local anesthetic effects of pheniramine and diphenhydramine, two histamine H₁ receptor antagonists, on spinal anesthesia and their comparison with lidocaine, a commonly used local anesthetic. After rats were injected intrathecally with
Ho Jun Lee et al.
Journal of Korean medical science, 24(5), 879-882 (2009-10-02)
The purpose of this study was to determine the effectiveness of antihistamine therapy for withdrawal movements caused by rocuronium injection. One hundred seventy one ASA I-II adults undergoing elective surgery were randomly assigned to one of two groups. Patients in
Tshering Lama et al.
Journal of telemedicine and telecare, 17(2), 105-108 (2010-12-09)
We describe a young woman from a rural village in Nepal who suffered multiple wasp and hornet stings. She collapsed and was managed by a telephone consultation between a village health worker and a hospital specialist. The patient recovered fully.
M R Louhaichi et al.
Talanta, 78(3), 991-997 (2009-03-10)
A new simple, rapid and sensitive liquid chromatographic method has been developed and validated for the simultaneous determination of pseudoephdrine, pheniramine, guaifenisin, pyrilamine, chlorpheniramine and dextromethorphan in cough and cold pharmaceuticals. The separation of these compounds was achieved within 13
Wenhua Gao et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 904, 121-127 (2012-08-21)
A rapid and efficient dual preconcentration method of on-line single drop liquid-liquid-liquid microextraction (SD-LLLME) coupled to sweeping micellar electrokinetic chromatography (MEKC) was developed for trace analysis of three antihistamines (mizolastine, chlorpheniramine and pheniramine) in human urine. Three analytes were firstly
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