P4354

Monoclonal Anti-p19^INK4d antibody produced in mouse

clone DCS-100, ascites fluid

• Sinónimos: Anti-INK4D, Anti-p19, Anti-p19-INK4D
• Número MDL: MFCD01324442
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• conjugado: unconjugated
• forma del anticuerpo: ascites fluid
• tipo de anticuerpo: primary antibodies
• clon: DCS-100, monoclonal
• mol peso: antigen 19 kDa
• contiene: 15 mM sodium azide
• reactividad de especies: human
• técnicas: immunocytochemistry: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; immunoprecipitation (IP): suitable; microarray: suitable; western blot: 1:1,000 using a cultured human tumor cell line extract
• isotipo: IgG1
• Nº de acceso UniProt: P55273
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CDKN2D(1032)

Descripción

Descripción general

Cyclin dependent kinase inhibitor 2D (CDKN2D), also referred to as p19INK4d, is part of the inhibitors of cyclin-dependent kinases (INK4) family. It consists of 166 amino acids and five ankyrin-like repeats that aid in protein-protein interactions. The gene encoding this protein is localized on human chromosome 19p13.

Especificidad

Shows no cross-reactivity with other closely related Cdk inhibitors, such as p15^INK4b, p16^INK4a and p18^INK4c.

Inmunógeno

recombinant human p19^INK4d.

Aplicación

Monoclonal Anti-p19INK4d antibody produced in mouse has been used in microarray.

Acciones bioquímicas o fisiológicas

Cyclin dependent kinase inhibitor 2D (CDKN2D) functions as a modulator of the cell cycle and has a role in DNA damage response. It acts as a chromatin accessibility factor. The protein associates with cyclin-dependent kinase 4 and 6 and inhibits their kinase activity.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable