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Merck

P4023

Sigma-Aldrich

Phenyl N-acetyl-α-D-galactosaminide

≥98%

Sinónimos:

Phenyl 2-acetamido-2-deoxy-α-D-galactopyranoside

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About This Item

Fórmula empírica (notación de Hill):
C14H19NO6
Número de CAS:
Peso molecular:
297.30
Número CE:
Número MDL:
Código UNSPSC:
12352201
ID de la sustancia en PubChem:

Ensayo

≥98%

temp. de almacenamiento

2-8°C

cadena SMILES

CC(=O)NC1C(O)C(O)C(CO)OC1Oc2ccccc2

Descripción general

Phenyl-N-acetyl-α-D-galactosaminide is a competitive inhibitor of N-acetyl-α-D-galactose and N-acetylneuraminic acid transferases.

Aplicación

Phenyl N-acetyl-α-D-galactosaminide has been used in a study to treat papillae in order to assess regeneration of broken tip links and restoration of mechanical transduction in hair cells. It has also been used in a study to inhibit N- and mucin-like O-glycosylation in order to investigate a novel transmembrane serine protease overexpressed in pancreatic cancer.

Código de clase de almacenamiento

13 - Non Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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H Sadeghi et al.
Glycobiology, 9(7), 731-737 (1999-06-11)
The human V2 vasopressin receptor contains one consensus site for N-linked glycosylation at asparagine 22 in the predicted extracellular amino terminal segment of the protein. This segment also contains clusters of serines and threonines that are potential sites for O-glycosylation.
C Wallrapp et al.
Cancer research, 60(10), 2602-2606 (2000-05-29)
We report the characterization of a novel serine protease of the chymotrypsin family, recently isolated by cDNA-representational difference analysis, as a gene overexpressed in pancreatic cancer. The 2.3-kb mRNA of the gene, named TMPRSS3, is strongly expressed in a subset
Y Zhao et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(26), 15469-15474 (1996-12-24)
A hair cell's tip links are thought to gate mechanoelectrical transduction channels. The susceptibility of tip links to acoustic trauma raises questions as to whether these fragile structures can be regenerated. We broke tip links with the calcium chelator 1,2-bis(O-aminophenoxy)
N Gross et al.
Medical and pediatric oncology, 36(1), 139-141 (2001-07-24)
CD44 represents a heterogeneous group of surface glycoproteins involved in cell-cell and cell-matrix interactions. CD44H is the major receptor for hyaluronate, and most if not all CD44H known functions are attributed to its ability to recognize hyaluronate. We have previously

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