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P3761

Sigma-Aldrich

Pentobarbital sodium salt

Sinónimos:

5-Ethyl-5-(1-methylbutyl)-2,4,6-trioxohexahydropyrimidine, Nembutal

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About This Item

Fórmula empírica (notación de Hill):
C11H17N2NaO3
Número de CAS:
57-33-0
Peso molecular:
248.25
EC Number:
200-323-9
MDL number:
MFCD00070198
UNSPSC Code:
41116107
PubChem Substance ID:
24898448

form

powder

drug control

USDEA Schedule II; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

solubility

H2O: soluble
alcohol: soluble

SMILES string

[Na].CCCC(C)C1(CC)C(=O)NC(=O)NC1=O

InChI

1S/C11H18N2O3.Na.H/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15;;/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16);;

InChI key

PGOYUXGHADTNIB-UHFFFAOYSA-N

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Application

Pentobarbital sodium salt has been used as an anesthetic in rats and mice prior to various in vitro studies.

Biochem/physiol Actions

Pentobarbital (PB) is a barbiturate and a ligand of the γ-aminobutyric acid subtype A (GABAA) receptor. It is a sedative anesthetic majorly used in rodent euthanasia. Pentobarbital possesses hypnotic functionality and muscle relaxing properties. It enhances GABAergic activity. Intraperitoneal injection of PB may result in loss of righting reflex (LORR) and heartbeat cessation.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Repr. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificados de análisis (COA)

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