P3493

Monoclonal Anti-Placenta Growth Factor-2 antibody produced in rat

clone 62526, purified immunoglobulin, lyophilized powder

• Sinónimos: Anti-PlGF-2
• Número MDL: MFCD02097209
• Código UNSPSC: 51111800
• NACRES: NA.41

Propiedades

• origen biológico: rat
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: 62526, monoclonal
• Formulario: lyophilized powder
• reactividad de especies: mouse
• técnicas: indirect ELISA: 0.5-1.0 μg/mL; neutralization: suitable; western blot: 1-2 μg/mL
• isotipo: IgG2a
• Nº de acceso UniProt: P49764
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: mouse ... Pgf(18654)

Descripción

Descripción general

The antibody neutralizes receptor-ligand interaction. The antibody shows no cross-reactivity with recombinant human PlGF and recombinant human VEGF.

Inmunógeno

purified recombinant mouse placenta growth factor 2 expressed in insect Sf 21 cells.

Acciones bioquímicas o fisiológicas

Placental growth factors (PlGF) are involved in the growth, migration and survival of endothelial cells. All the four isoforms identified are expressed in placenta and umbilical vein endothelial cells. PlGF bind to specific Flt-1 receptors that result in activation and recruitment of dendritic cells, smooth muscle cells and inflammatory cells. PlGF2 has the ability to bind heparin while PlGF1 is a soluble isoform.

Forma física

Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline with 5% trehalose.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)